The Ingredients

Why a multi-pathway approach works

Insomnia isn’t caused by one factor. It’s a mix of mental overstimulation, cortisol imbalance, poor neurotransmitter production, and disrupted sleep architecture.
Many products mask this with sedatives or synthetic melatonin. Lyra does it differently: it restores balance from within, respecting how the human body is meant to sleep.Our scientific team carefully selected and dosed 13 proven ingredients to address stress, calm the mind, promote natural neurotransmitter flow, and support healthy deep sleep — with zero external melatonin.

L-Theanine (200 mg)

An amino acid most abundant in green tea leaves. L-Theanine naturally raises alpha brain waves, the same patterns seen in calm wakefulness and pre-sleep states. It works within 30–60 minutes to settle intrusive thoughts without causing drowsiness.

Gamma-Aminobutyric Acid (GABA) (200 mg)

As the main inhibitory neurotransmitter, GABA acts as a ‘brake’ for an overactive mind. Supplemental GABA, when used with L-Theanine and adaptogens, amplifies the calming signal, helping the brain shift from hypervigilance to relaxation.

Magnesium Bisglycinate (100 mg elemental)

Crucial for over 300 enzymatic reactions in the body, magnesium also modulates the GABAergic system. Bisglycinate is the most absorbable chelated form, ensuring gentle yet effective relaxation of both muscles and neurons.

5-HTP (100 mg)

By directly increasing serotonin, 5-HTP helps re-establish a healthy mood and acts as a precursor for your body’s own melatonin, eliminating the need for a synthetic substitute. Clinical doses start at 50–100 mg, making Lyra’s 100 mg both safe and effective.

Ashwagandha Extract (100 mg)

This adaptogen is standardized for withanolides, the active compounds proven to reduce cortisol and mitigate chronic stress. Ashwagandha supports a balanced HPA axis (hypothalamic-pituitary-adrenal axis), the body’s core stress response system.

Saffron Extract (30 mg)

One of the world’s most valuable botanicals. Saffron is increasingly studied for its unique mood-brightening effect and its ability to reduce mild anxiety. Together with 5-HTP, it enhances serotonin pathways, reinforcing emotional calm before bed.

Lavender Flower Extract (50 mg)

Beyond its aroma, standardized lavender extract has demonstrated mild sedative and anxiolytic actions. It subtly reduces sleep onset latency — the time it takes to transition from wakefulness to sleep.

Passionflower Extract (75 mg, 10:1 concentrate)

A concentrated botanical known to boost natural GABA levels and reduce nighttime mental chatter. Passionflower is especially useful for people who struggle to quiet their minds despite physical tiredness.

Hops Flower Extract (50 mg, 10:1 concentrate)

Works synergistically with passionflower and lavender to deepen sleep architecture. Traditionally used in herbal medicine to promote calm and aid sleep onset.

Glycine (150 mg)

A simple amino acid with powerful benefits for sleep quality. Glycine slightly lowers core body temperature, a natural signal for sleep readiness. It also supports REM and deep sleep phases, resulting in more restorative cycles.

Vitamin B6 (5 mg, Pyridoxal-5-Phosphate)

B6 is a cofactor required for the synthesis of serotonin and GABA. Lyra uses the active P5P form, ensuring the vitamin is readily usable by the body without conversion steps.

Vitamin B12 (100 mcg, Methylcobalamin)

Essential for healthy circadian rhythm and optimal brain function. This methylated form of B12 is better absorbed and supports waking energy, helping counteract morning fatigue.

Magnolia Bark Extract (40 mg)

Rich in bioactive honokiol and magnolol. These compounds gently bind to GABA receptors, offering additional stress reduction and helping to curb night-time cortisol surges that often trigger 2–3 AM wake-ups.

Why synergy matters

Individually, each ingredient has peer-reviewed evidence of effectiveness. Combined at therapeutic doses, they complement and potentiate each other’s actions.

This is what sets Lyra apart:

  • No dependency cycle like synthetic melatonin
  • No excessive sedation
  • No morning grogginess
  • Just a gradual rebalancing of the body’s sleep system — safely and sustainably.

Your Sleep, Reclaimed by Science

Lyra Nocturne™ is more than a sleep aid. It’s a nightly ritual to restore what modern stress has stolen: true, deep, restorative sleep that empowers you to wake clear, calm, and fully alive.